Description

MOTS-c – Mitochondrial Metabolic & Longevity Research Peptide

MOTS-c 10 mg is a 16-amino-acid peptide encoded by mitochondrial DNA (mtDNA) within the 12S rRNA gene. It functions as a mitochondrial-derived signaling molecule that regulates metabolic balance, insulin sensitivity, and cellular stress adaptation. By activating AMPK and modulating metabolic gene expression, MOTS-c supports studies on aging, metabolic health, endurance, and mitochondrial performance.

This peptide has gained significant interest in longevity research for its ability to mimic exercise-like metabolic effects, improve glucose homeostasis, and enhance cellular resilience under stress.

Key Features & Research Applications

⚡ Mitochondrial Metabolic Regulation:
Activates AMPK and boosts energy efficiency, improving glucose utilization and lipid metabolism.

🏃 Exercise Mimetic Properties:
Replicates molecular effects of endurance training, enhancing performance and endurance in preclinical models.

🧬 Anti-Aging & Longevity Research:
Regulates mitochondrial function and gene expression linked to healthy aging and cellular protection.

💪 Insulin Sensitivity & Fat Oxidation:
Improves insulin response and promotes fat metabolism, making it valuable in obesity and diabetes research.

🧠 Cellular Stress Adaptation:
Enhances resistance to oxidative and metabolic stress by improving mitochondrial signaling pathways.

Product Details

• Name: MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c)

• Form: Lyophilized powder

• Sequence (16 aa): Met–Arg–Trp–Gln–Glu–Met–Gly–Tyr–Gly–Lys–Met–Arg–Arg–Ile–Phe–Tyr

• Molecular Formula: C₁₄₉H₂₆₀N₄₄O₄₆S

• Molecular Weight: ~2,037 Da

• Purity: ≥ 98% (HPLC verified)

• Dosage Strength: 10 mg per vial

• Appearance: White to off-white lyophilized powder

• Storage: Store in a cool, dry environment; refrigerate (35.6–46.4°F) after reconstitution; avoid freeze–thaw cycles.

• Packaging: Sterile, sealed vial for laboratory use.

• Verification: Third-party tested for identity and purity.