Description

Kisspeptin-10 – Reproductive Axis & Endocrine Research Peptide

Kisspeptin-10 5 mg is the C-terminal decapeptide fragment of human kisspeptin (KISS1), the principal upstream activator of the hypothalamic-pituitary-gonadal (HPG) axis. Acting via the KISS1R (GPR54) receptor on GnRH neurons, Kisspeptin-10 robustly stimulates gonadotropin-releasing hormone (GnRH), leading to downstream LH/FSH secretion. It is widely used in research on fertility, puberty onset, reproductive endocrinology, and neuroendocrine regulation.

Key Features & Research Applications

🧠 GnRH Stimulation & HPG Axis Activation
Directly activates KISS1R to trigger GnRH pulses and increase pituitary LH/FSH secretion.

🧬 Fertility & Puberty Research
Valuable in studies of hypothalamic amenorrhea, delayed/precocious puberty models, and oocyte-maturation protocols.

⚖️ Endocrine Regulation
Enables controlled investigation of sex-steroid feedback loops, cycle dynamics, and reproductive hormone profiling.

🔬 Neuroendocrine Mechanisms
Supports work on peptide receptor signaling, pulse frequency modulation, and hypothalamic network plasticity.

Product Details

• Name: Kisspeptin-10 (Human, amidated)

• Form: Lyophilized powder

• Sequence (10 aa): Tyr–Asn–Trp–Asn–Ser–Phe–Gly–Leu–Arg–Phe–NH₂ (YNWNSFGLRF-NH₂)

• Molecular Weight: ~1,302 Da

• Purity: ≥ 98% (HPLC verified)

• Dosage Strength: 5 mg per vial

• Appearance: White to off-white lyophilized powder

• Storage: Store dry at 35.6–46.4°F; after reconstitution, aliquot and freeze at −4°F; avoid repeated freeze–thaw

• Solubility: Sterile water or mild aqueous buffers; gentle agitation recommended

• Packaging: Sterile, sealed research-grade vial

• Verification: Third-party tested for identity and purity