Melanotan 1 – Melanocortin & Skin Pigmentation Research Peptide

Melanotan 1 10 mg (also known as Afamelanotide) is a synthetic analog of the alpha-melanocyte-stimulating hormone (α-MSH), designed to activate the melanocortin-1 receptor (MC1R). This activation increases melanin production (melanogenesis) in the skin, leading to enhanced pigmentation and protection against UV radiation.

Melanotan 1 is primarily used in research exploring skin pigmentation, photoprotection, DNA repair, and melanocortin receptor biology, as well as potential therapeutic applications in conditions like vitiligo and erythropoietic protoporphyria (EPP).

Key Features & Research Applications

🌞 Melanin Production & Photoprotection:
Stimulates melanogenesis in melanocytes, resulting in increased pigmentation and enhanced protection against UV-induced DNA damage.

🧬 DNA Repair & Cellular Defense:
Enhances natural UV defense mechanisms by reducing oxidative stress and supporting DNA repair enzymes.

🩹 Dermatological Research:
Used in studies on pigmentation disorders such as vitiligo and photodermatoses.

❤️ Anti-Inflammatory & Antioxidant Effects:
Exhibits cytoprotective and anti-inflammatory activity via melanocortin receptor pathways.

🧠 Melanocortin System Research:
Supports studies on receptor subtype signaling (MC1R–MC5R) and neuroendocrine regulation.

Product Details

• Name: Melanotan 1 (Afamelanotide)

• Form: Lyophilized powder

• Sequence (13 aa): Ac–Ser–Tyr–Ser–Nle–Glu–His–D–Phe–Arg–Trp–Gly–Lys–Pro–Val–NH₂

• Molecular Formula: C₇₈H₁₁₁N₂₁O₁₉

• Molecular Weight: ~1646.9 Da

• Purity: ≥ 98% (HPLC verified)

• Dosage Strength: 10 mg per vial

• Appearance: White to off-white lyophilized powder

• Storage: Store in a cool, dry environment; refrigerate (35.6–46.4°F) after reconstitution; avoid repeated freeze–thaw cycles.

• Solubility: Sterile water or bacteriostatic saline; mix gently until fully dissolved.

• Packaging: Sterile, sealed research-grade vial

• Verification: Third-party tested for identity and purity